You probably know Lenny and Squiggy from Laverne and Shirley. What you maybe didn't know is that Lenny and Squiggy didn't begin with that. Or end there. Or that they were musical.
Michael McKean was Lenny, and he went on to fame and recognition as part of Spinal Tap and later movies with Christopher Guest, and David Lander was Squiggy. His career was sadly cut short by Multiple Sclerosis, the story of which he told in his book Falling Down Laughing: How Squiggy Caught Multiple Sclerosis And Didn't Tell Nobody.
The two were friends and comedy partners with a few different characters they would play off the cuff in nightclubs and stuff in the 70's. They were friendly with Penny Marshall, who recommended that they play Lenny and Squiggy on their show and the rest was history.
They even released an album as Lenny and Squigtones. It's elusive and expensive, but you can hear the tunes here and there if you know where to look.